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Description
Under hypoxic conditions, human macrophages inhibit ferritin autophagy by reducing the expression of nuclear receptor coactivator 4 (NCOA4), resulting in increased mitochondrial ferritin expression and decreased intracellular free iron, thus regulating ferroptosis [35]
C a ch ca hng r rng
Knowledge of these adverse drug-mitochondrial interactions is important in assisting clinicians to design safer therapeutic regimens
Each assay utilized its own calibration standard
doi: 10.1080/19440049.2014.941947
