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However, by limiting the gene deficiency only to mammary gland tissue using a Cre-LOX strategy, investigators were able to generate mouse models to study breast cancer in adults by overcoming the embryonic lethality associated with the original knockout line of mice (Xu 1999)

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Li et al used tetrahedral framework nucleic acid (tFNA) to synthesize tFNA-Cur, a nanoparticle that can deliver the natural compound curcumin to the bone marrow, thereby enhancing the bioavailability and stability of curcumin

ME/CFS lacks standardised diagnostic criteria owing to variations in both inclusion and exclusion criteria across different diagnostic guidelines, and furthermore, there are currently no effective treatments available