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When the terminal ileum is surgically removed, as is often the case in individuals with inflammatory bowel disease, colorectal cancer, familial adenomatous polyposis, or other conditions requiring ileostomy or pouch formation, but also urostomy, B12 absorption may become severely compromised

Peptides degrade through several distinct chemical pathways, each influenced by storage conditions in predictable ways

Neuropathic pain affects 7% to 10% of people in the general population, but it is much higher in people with diabetes between 20% and 30% (Baskozos et al., 2023)

Common side effects of peptide therapies include gastrointestinal discomfort, such as nausea and diarrhea, particularly with GLP-1 receptor agonists