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Creatine in Health and Disease. Nutrients , January 2021, Perna, Simone et al
Analysis of the feedback loops shows that the regulatory system is extremely complex

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Of 340 eligible patients, 275 (81%) could be followed up

observed that a regimen inclusive of vitamin E led to augmented sperm concentration and diminished DNA damage in infertile patients, although the motility and morphology remained largely unchanged [78]
