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Posterior fossa choroid plexus tumors are divided into posterior fossa type A and posterior fossa type B groups based on DNA methylation profiles, with the PFA group occurring mainly in infants and toddlers with a worse prognosis and the PFB group primarily in older children or adults with a relatively better prognosis [50, 51]

Nat Rev Cancer (2012) 12(8):56471

Acknowledgments The authors thank Professor Z.J

However, CI showed no activation upon substrate injection (pyruvate + malate) in Gclc -deficient FoB (Fig

doi: 10.2217/nnm-2018-0417 [DOI] [PubMed] [Google Scholar] 74.Hasan N, Imran M, Kesharwani P, et al