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Vigorous shaking, touching the stopper with bare hands, or improper water use can lead to peptide degradation and inaccurate concentrations, which may result in side effects

Clinical studies have demonstrated that tirzepatide can lead to significant improvements in blood sugar control by increasing insulin secretion in response to food and reducing glucose release from the liver

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Furthermore, a phase III trial (PROCEED) was suspended after a prespecified interim futility analysis revealed a lack of benefit in PFS (NCT 01170650)

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