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However, the field still lacks preclinical models that preserve this patient-specific biology while allowing functional testing of candidate mechanisms and targets

[150] develop a novel ionizable lipid, 4N4T, to create LNPs (4N4T-LNPs) that enhance mRNA translation efficiency compared to SM-102-LNPs

Bureau, C

Phenotypic expression of a novel C282Y/R226G compound heterozygous state in HFE hemochromatosis: molecular dynamics and biochemical studies

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