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Woozy mouse skeletal muscle confirmed the enhancement of the SOD/CAT antioxidant system and the reduction of lipid peroxidation To validate the results obtained in the fibroblasts isolated from a patient with MSS, we examined the SOD/CAT antioxidant system and the level of oxidative damage in the skeletal muscle of the woozy mouse, a representative model of MSS
Pharmacological inhibition of XO (e.g., allopurinol) demonstrates marked hypouricemic effects, underscoring the clinical significance of this pathway (Yang et al., 2024)
doi: 10.1016/j.mrrev.2015.07.003
