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The device worked by pressure from a syringe plunger, which pushed the fluid down the tube and past the concentric ring tip where the flow was converted into a thin mist that exited the applicator at the entrance to one nostril directly into the nasal cavity

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[DOI] [PMC free article] [PubMed] [Google Scholar] 15.Korakas E., Ikonomidis I., Kousathana F., Balampanis K., Kountouri A., Raptis A., Palaiodimou L., Kokkinos A., Lambadiari V