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Sci Rep 12:15869 [DOI] [PMC free article] [PubMed] [Google Scholar] 148.Rahimi Darehbagh R, Seyedoshohadaei SA, Ramezani R, Rezaei N (2024) Stem cell therapies for neurological disorders: current progress, challenges, and future perspectives

however, there has been a gradual increase in the incidence of this disease among children and adolescents in recent times [105, 106]

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However, there is a small subset of patients that does not obey this pattern, displaying median expression of NRF2 and low expression of KEAP1 red dots (NRF2-KEAP1 alteration) indicating a higher activity of the transcription factor in those tumors