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This is one of the core pathological mechanisms underlying obesity, diabetes, and other metabolic diseases
Bilirubin is a brownish substance that gives the skin the yellowish tone that is characteristic of jaundice
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Mitochondrial sirtuin 3 (SIRT3) is a major modulator of mitochondrial metabolism and homeostasis, regulating UPR mt , mitochondrial biogenesis, mitophagy, fusion/fission, and antioxidant expression 98
