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The reaction is catalyzed by the carnitine acetyltransferase (CrAT, EC:2.3.1.7), which is present in many cell compartments, including the cytosol, the matrix or mitochondria and peroxisomes, as well as the endoplasmic reticulum and nucleus [5, 83, 106]

Kossoff, E

Behaviorally, the LAC treatment during the last part of chronic restraint stress (CRS) enhanced resilience and reversed the effect of CRS, which is shown by increased social interaction and reduced passive behavior in a forced swim test ( Disorders of metabotropic glutamate (mGlu) receptors and neurotrophins have significant negative effects on neuroplasticity, leading to depression, but LAC regulate brain type 2 metabotropic glutamate (mGlu2) receptors and N-methyl-D-aspartic acid (NMDA) receptors to induce antidepressant effect ( Neurotrophic factors are associated with the pathogenesis of depression (9395)

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Since plasma LC elevates following 2 weeks of supplementation [21, 22], short protocols of supplementation may be considered as effective in attenuating post-exercise muscle soreness