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Vitamin E also works synergistically with glutathione to enhance its antioxidant effects

Accordingly, effective regulation of HIF to sustain lipid homeostasis and thereby generate ferroptotic responses is essential

A study has confirmed that the expression of glycolysis-related genes in tumor samples from patients with melanoma and non-small-cell lung cancer is negatively correlated with T cell infiltration, and that tumor glycolysis is related to the efficacy of adoptive T cell therapy (ACT), suggesting that the glycolytic pathway may be a candidate target for combined therapeutic intervention (283)

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One way methionine may contribute to inflammation is through the generation of homocysteine, a toxic amino acid that can damage cells and tissues [45]