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Rising haemoglobin and normalisation of mean cell volume usually become evident within one to two weeks, with full blood count (FBC) monitoring recommended after approximately 2 weeks and again after 810 weeks to confirm response

This precaution helps prevent any unforeseen interactions and ensures safe use of the injection alongside other treatments

However, it may take several weeks or months for full recovery

According to NICE guidance and standard UK clinical practice, patients with confirmed B12 deficiency and neurological symptoms typically require initial treatment with hydroxocobalamin injections

The dose is usually 1,000 mcg