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2 Anatomy of the intervertebral disc and degeneration The intervertebral disc (IVD) is a fibrocartilaginous structure located between adjacent vertebral bodies, composed of the outer annulus fibrosus (AF), the central nucleus pulposus (NP), and the superior and inferior cartilage endplates (CEP)

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Complexation with -CD ensured a high solubility and stability of the drug in the acidic environment of the stomach [87]

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