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The methylated version of B12 can bypass some of the processing required by the body in order for utilization

The peptide is stable in gastric acid, which makes oral administration viable for gut-targeted applications, a property that distinguishes it from many other therapeutic peptides that degrade before reaching target tissue

First, polar aggregation induced by an armed mAb results in a significant re-distribution of CD38 on the membrane and a marked reduction in its expression