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NNMT is upregulated in adipose tissue in obesity, and its inhibition is studied as a potential strategy to modulate NAD+ metabolism and metabolic gene expression

364 found that Exos from BM-MSCs ameliorated functional deficits via the enhancement of oligodendrocyte progenitor cell differentiation, remyelination, the modulation of microglial polarization, and a reduction in the inflammatory response in the CNS

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This was a randomized, double-blind, placebo-controlled clinical study in which participants were randomly assigned to the line-targeting peptide serum (LTPS) arm or the placebo serum arm

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