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Abbreviations ABCs: Age-associated B cells AID: Activation-induced cytidine deaminase ART: Antiretroviral therapy CAR-T: Chimeric antigen receptor T-cell cGPDH: Glycerol-3-phosphate dehydrogenase CMV: Cytomegalovirus CpG: Cytosine-phosphate-Guanine D + Q: Quercetin and dasatinib DCs: Dendritic cells DN: Double-negative DP: Double-positive E47: Transcription factor E47 FFAR4: Free fatty acid receptor 4 GCA: Grancalcin GLUT1: Glucose transporter 1 GSH: Glutathione GVHD: Graft-versus-host disease HSCs: Haematopoietic stem cells HSPCs: Haematopoietic stem/progenitor cells INSTIs: Integrase strand transfer inhibitors iPSCs: Inducing pluripotent stem cells KIR: Killer-cell immunoglobulin-like receptors KLRG1: G1-Killer cell lectin-like receptor subfamily G member 1 LYVE1: Lymphatic Vessel Endothelial Hyaluronan Receptor 1 mDCs: Myeloid dendritic cells METTL3: Methyltransferase-like 3 mtDNA: Mitochondrial DNA mTOR: Mechanistic target of rapamycin NAD: Nicotinamide adenine dinucleotide NK: Natural killer cell NMN: Nicotinamide mononucleotide NNRTIs: Non-nucleoside Reverse Transcriptase Inhibitors NR: Nicotinamide riboside NRTIs: Nucleoside Reverse Transcriptase Inhibitors P2X7: P2X purinoceptor 7 PAMPs: Pathogen-associated molecular patterns pDCs: Plasmacytoid dendritic cells PHS: Phytosphingosine PIs: Protease Inhibitors PRRs: Pattern recognition receptors PWH: People with HIV ROS: Reactive oxygen species RTEs: Recently emigrated thymocytes RUNX3: Runt-related transcription factor 3 SASP: Senescence-associated secretory phenotype SA--Gal: Senescence-associated beta-galactosidase SHMT2: Serine hydroxymethyltransferase 2 SIV: Simian immunodeficiency virus TCR: T-cell receptor TEMRA: Terminally Differentiated Effector Memory T Cells ThPOK: T helper-inducing POZ/Krueppel-like factor TLR: Toll-like receptors TRE: Time-restricted eating TRIB2: Tribbles pseudokinase 2 T1: Thymosin alpha 1 uPAR: Urokinase-type plasminogen activator receptor VOCs: Volatile organic compounds Vpr: HIV-1 viral protein R ZEB2: Zinc finger E-box-binding homeobox 2 -KG: Alpha-ketoglutarate m: Mitochondrial membrane potential References UNAIDS

doi: 10.3389/onc.2014.00381 101 HeMChenSYuHFanXWuHWangYet al

Although the great bulk of research has concentrated on understanding the impact of cellular signaling pathways, the epigenetic interactions between MSCs and OC remain largely unexplored

Additionally, the host environment enables recapitulation of anatomical characteristics of brain tumors such as angiogenesis, invasiveness, hypercellularity, and necrosis 47,80

Research published in the Journal of Orthopaedic Research examined tendon-to-bone healing in rat Achilles tendon models