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[DOI] [PubMed] [Google Scholar] 391.Sakurai Y., Kubota N., Kadowaki T

The coefficient of determination, R 2 , provides an estimate of the proportion of variance in the response variable explained by the model

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HIF-1, in particular, exerts dual effects: while its activation can provide anti-inflammatory and neuroprotective benefits, as observed in stroke models [356], its sustained upregulation correlates with impaired synaptic plasticity and memory deficits [74, 75]

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