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Similarities between insulin and IGF-1 suggest the possible role of IGF-1 in the pathological process of this syndrome, therefore several studies have attempted to correlate IGF-1 plasma levels with MetS

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This could mean that two children with the same 25(OH)D concentration might have different neurodevelopmental outcomes if one has a VDR/DBP variant that impairs vitamin D signaling

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PeptideReceptor Interaction Research: Scientists analyze receptor binding characteristics and signaling behavior in experimental peptide models