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The committee suggests that estimating an RfD would provide useful guidance to risk managers to help them (1) assess potential health risks in that portion of the population with intakes above the RfD, (2) assess risks to population subgroups, such as those with occupational exposures, and (3) estimate the contributions to risk from the major food sources and other environmental sources of TCDD, other dioxins, and DLCs for those individuals with high intakes

While effective for glycemic control and weight management, these mechanisms can limit nutrient intake and affect absorption

10.1016/j.bbrc.2004.11.012 Biochem

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