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However, IDH2 overexpression failed to decrease mRNA levels of SASP genes (IL-1, IL-6, CCL2 and MMP9) in ECs from old mice

This diagnostic power extends to biomarkers

Interaction of nobiletin with methotrexate ameliorates 7-OH methotrexate-induced nephrotoxicity through endoplasmic reticulum stress-dependent PERK/CHOP signaling pathway

Detachment of cytochrome c from cardiolipin might also be triggered by increased cytosolic calcium, which weakens the electrostatic interaction between cytochrome c and cardiolipin and further generates ROS via MPT

Negatively charged nanoparticles have superior tolerability in comparison to their positively charged particles [135]