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Mechanistically, we found that Usp2 deletion was associated with decreased protein levels of TFRC and TXNDC5, alongside enhanced ubiquitination of these targets in the kidneys post-UUO (Fig
After obtaining spectral libraries for bright light images of unlabeled tissue and neuromelanin and fluorescent images of fluorophores and background autofluorescence, brightfield and fluorescent images were "unmixed" into individual signal components (i.e
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There is a reciprocal regulatory relationship between mTOR and AMPK, and activation of mTOR inhibits AMPK
Schlossman and E.L
