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Introduction Environmental factors including pollution, smoke, ultraviolet rays, and diet can cause damage to somatic cells due to the production of high amounts of reactive oxygen species (ROS)-mediated oxidative stress [1]

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Additionally, study participants with vitamin B12 deficiency and tinnitus reported a reduction in tinnitus symptom severity following therapy with vitamin B12 injections

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Pyruvate kinase (encoding by pykF ) catalyzes phosphoenolpyruvic acid (PEP) to form pyruvate and is a rate-limiting enzyme in the glycolysis pathway