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In this study, we characterized the changes in neural functionality, secreted cytokine profiles, and gene expression in co-cultures of human iPSC-derived neurons and primary astrocytes in response to prolonged exposure to TNF- and IL-6

Avan A, Quint K, Nicolini F, Funel N, Frampton AE, Maftouh M, et al

Always inform your healthcare provider if you have allergies to vitamins or any other medications you are taking

Claims otherwise should be viewed with skepticism

Patients with NTRK fusions should receive larotrectinib or entrectinib with serial ctDNA or tissue sequencing at progression to identify resistance mutations guiding selitrectinib-based salvage