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Lower limits of quantification (LLOQs) were calculated for all 8 analytes

All procedures were conducted in accordance with the ethical standards of the institutional research committee and with the principles outlined in the Declaration of Helsinki

The patients were divided into two groups: those at risk for cardiovascular disease because of a glucose disposal rate less than or equal to 7.9 milligrams per kilogram of bodyweight (16 patients) and those with a glucose disposal rate greater than 7.9 mg/kg/bw (16 patients)

It is not a stimulant like caffeine, but if you are sensitive to supplements, you may prefer morning or midday doses so your sleep pattern remains undisturbed