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The unique characteristics of tumor vasculature and preclinical evidence for its selective disruption by tumor-vascular disrupting agents

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Collagen remodeling, extracellular matrix repair, and tendon adaptation require amino acids and micronutrients

Direct Effects Effects of growth hormone itself include: Lipolysis released fatty acids are used to generate ATP, thereby sparing glucose Glycogenolysis in the liver glycogen is broken down to glucose, raising blood glucose levels with a diabetogenic effect Epithelial and connective tissue growth and repair by stem cell division and differentiation Indirect Effects The effects of IGF-1 can be thought of as anabolic (compound building), similar to insulin

doi: 10.1007/s11060-013-1346-5