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doi: 10.1016/j.atherosclerosis.2018.07.014 [DOI] [PubMed] [Google Scholar] 132

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KLF2 regulates eNOS uncoupling via Nrf2/HO-1 in endothelial cells under hypoxia and reoxygenation

The human body uses oxygen as the primary oxidant in energy producing biological reactions, yet this aerobic mechanism is associated with the generation of highly reactive and potentially harmful (free radical) molecules