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Intralesional corticosteroids

TB-500 suppresses pro-inflammatory cytokines (TNF-, IL-1) while increasing anti-inflammatory mediators like IL-10, leading to decreased immune-mediated tissue damage

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CLA-DY can also catalyze the reduction of 11( E )-10-oxo-OME into 11( E )-10-HOME, which is dehydrated by CLA-HY into two conjugated-LA compounds 9( Z ),11( Z )-ODE and 9( E ),11( Z )-ODE (Scheme 22)