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In our series, patients with NAs were present in at least 50% of patients with confirmed NF1.5 Possibly, the difference in prevalence in the different studies, which ranges from 8.8% to 51%,3 is a result of the retrospective or prospective study design as these lesions are difficult to diagnose unless sought systematically

When comparing first-in-human trials vs Phase 1 clinical studies you will see a difference in design

J Eur Acad Dermatol Venereol 32(6):10281033

Carrier rates are 58 percent in sub-Saharan Africa but between 8 and 15 percent of babies become infected in some parts of the world, thus routine immunization is recommended

In the context of cerebral hemorrhage ischemia-reperfusion injury, the action of RSL3 has been found to worsen the incidence of ferroptosis (133)