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J Biol Chem (2010) 285:2263950

Critically, MP201-treated mice exhibited improved novel object recognition, reduced cortical lesion volume and increased hippocampal neuron density two weeks after TBI [77]

BM-hMSC-derived NGF was also reported to enhance hHSC apoptosis by inhibiting nuclear factor kappa B (NF-B) and the expression of the anti-apoptotic gene Bcl-xl [188]

Therefore, it is recommended that individuals at an elevated risk of bleeding, those taking specific anticoagulants and antiplatelet agents, and those undergoing surgical or other invasive operations should avoid it (Rosenblatt and Mindel, 1997)
