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Inhibition of the Intrinsic NAD+ Glycohydrolase Activity of CD38 by Carbocyclic NAD Analogues

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while neither compound is known to impair lactation, the concentrated doses delivered by weekly injections may alter milk taste or infant gastrointestinal tolerance

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Besides, the CD38 low/- NK cells engineered by CRISPR/Cas9 system is another method to maintain NK cell function during Daratumumab therapy