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A concern that TCI can increase lymphomas and skin cancer has been refuted epidemiologically, and TCI were not seen to enhance the risk when used for long durations

Mendoza N, Diaz-Ropero MP, Aragon M, et al

Alterations in the structure and function of mitochondrial compartments affect mitochondrial homeostasis and quality control (Iovine et al., 2021), which are closely linked to neurological diseases (Figure 1)

EMT is a multi-step process in which epithelial cells lose their characteristic traits and gain mesenchymal features, including the loss of cell junctions and apicobasal polarity [33]