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Inactivation of GPX4 leads to an accumulation of lipid peroxides, resulting in ferroptotic cell death
To the best of my knowledge, no specific nephrotoxicity has been reported in the many preclinical and current clinical trials [104]

MOTS-c can be added for metabolic optimization and mitochondrial support
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[DOI] [PubMed] [Google Scholar] 165.Heurteaux C., Lauritzen I., Widmann C., Lazdunski M

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