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Ideally , antiseizure medications would be added simultaneously, combining steps #1 and #2 into a single step
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Most pharmacogenomic risk factors for DILI reside in the HLA region on chromosome 6 and are often drug-specific

(11) Elena M Khvatova, Victor N Samartzev, Pavel P Zagoskin, Igor A Prudchenko, and Inessa I Mikhaleva (2003) Delta sleep inducing peptide (DSIP): effect on respiration activity in rat brain mitochondria and stress protective potency under experimental hypoxia Peptides, 2003 Feb, Volume 24 (Issue 2), Pages 307-11

Acta Pharm Sinica
