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Description
M1 macrophages are primarily characterized by enhanced glycolysis, pentose phosphate pathway activity, and fatty acid synthesis, with a disrupted tricarboxylic acid cycle leading to the accumulation of metabolites such as succinate and citrate (79) ( Figure 3 )

Oral supplements rely on digestion and absorption, which may be limited for some patients

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Peptide effects on osteoblasts: Growth hormone peptides increase systemic IGF-1 which directly stimulates osteoblast proliferation and activity

K., Jang S
