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Clin Exp Immunol (2001) 126:41220

At the same time, ROS increase in cytosol plays a significant role in cytoskeleton remodeling ( Skin carcinogenesis and exposure to UVA: the ultraviolet component A sunlight (UV-A with the wavelength 320400 nm) has the potential to generate oxidative stress in cells and tissues, so that endogenous and exogenous antioxidants strongly influence the biological effects of UVA (Sage et al., 2012)

P-glycoprotein (P-gp) plays a role in ACs efflux transport, though some studies report low permeability without significant efflux activity (Gao et al

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The results showed that GHK-Cu significantly improved skin sagging, transparency and appearance, and reduced the depth of fine lines and wrinkles compared with placebo