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Rapamycin, an inhibitor of mTOR, abolishes LPS-induced IL-10 induction in murine DCs, which leads to increased IL-12 levels, as IL-10 inhibits the production of IL-12 in an autocrine manner 49

Due to this condition, it is known to be associated with increased risk of stomach cancer

[DOI] [PMC free article] [PubMed] [Google Scholar] 31.El Asmar R, Panigrahi P, Bamford P, Berti I, Not T, Coppa GV, Catassi C, Fasano A

One can presume that processes initiated by transcription factors during the first hours of therapy of ischemized animals were developing further