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2. Musculoskeletal Regeneration

Small molecule drug discovery approaches mainly focus on protein-ligand interactions that have a much smaller contact area in comparison to the larger featureless interface areas commonly found with PPIs, which also lack the traditional endogenous small molecular ligands used for reference in small-molecule drug discovery

Frequency varies by patient and goal

Vitamin B12 is a cofactor of methionine synthase and L-methylmalonyl-CoA mutase, which is involved in the metabolism of homocysteine and methylmalonic acid metabolism

Common signs include fatigue, muscle or joint pain, skin rashes, and digestive issues