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However, in the context of elevated vitamin C uptake, high vitamin C can act as a pro-oxidant by reducing iron and promoting lipid peroxidation, GPX4 inactivation, and ferroptotic cell death 125
Treatment for vitamin B12 deficiency typically involves oral supplements, with doses ranging from 1000 to 2000 mcg per day
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Understanding these mechanisms is critical for developing targeted therapeutic interventions to mitigate immune dysregulation and improve clinical outcomes in patients with HIV/AIDS
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