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doi:10.1159/000053183 Wilding JPH, Batterham RL, Calanna S, et al

Most patients starting with normal b12 levels and no significant risk factors do not require supplementation

Before starting, confirm that the vial label is correct and shows no signs of tampering

Most clinics use 12 to 16 week trials with weight, body composition (DEXA where available), and side effect monitoring
