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Following colonization, probiotics further suppress pathogens through ecological and chemical mechanisms, including localized nutrient depletion and secretion of antimicrobial compounds such as bacteriocins (Kommineni et al., 2015)

Ozone: Sci Eng 43(5):427435

EXOs are thought to engage with endocrine and paracrine systems that regulate homeostasis (Xiong et al., 2023)

Diabetes Care 34, 20542060.10.2337/dc11-0503 194 ZoccaliC.Bode-BgerS.MallamaciF.BenedettoF.TripepiG.MalatinoL.CataliottiA.BellanuovaI.FermoI.FrlichJ.BgerR

As illustrated, multiple mechanisms are involved with the pleiotropic abilities of melatonin that not only have been shown to have antioxidant, inhibition of oxidative stress, and anti-inflammatory effects but also in inducing vasodilation, cardio-protective, cancer-protective, and benefits in respiratory diseases