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[DOI] [PubMed] [Google Scholar] 335.Ismail T, Shafi S, Srinivas J, et al

Moisturizes and hydrates the skin

At the top, a circular folate cycle shows tetrahydrofolate (THF) being converted to 5,10-methyleneTHF and then to 5-methylTHF in a riboflavin-dependent reaction

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As an alternative strategy to avoid fibrillation, we explored N -methylations of the backbone amides because it could lend more conformational freedom and retain the original human amylin sequence in comparison with introducing the proline residues