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In PD patients, reduced BH4 levels and GCH1 activity in the SN and striatum are associated with PD progression, indicating that aberrant BH4 metabolism contributes to PD pathogenesis (105)

Ehlers-Danlos Syndrome (EDS) encompasses a group of genetic connective tissue disorders marked by joint hypermobility, easily bruised skin, and tissue fragility

Thioredoxin reverses age related hypertension by chronically improving vascular redox and restoring eNOS function

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Western blots, activity gels and activity assays are various methods used to determine protein and activity in both cells and tissue depending on the amount of protein required for each assay