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AP-1 and NF-B induce the expression of multiple genes involved in inflammation and oxidative stress response, cell death and fibrosis, including proinflammatory cytokines such as tumor necrosis factor- (TNF-), interleukin-1 and interleukin-6 and growth factors such as PDGF and TGF-

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While the above-mentioned findings (summarized in Table 1) are very promising, it is important to note that studies on the potential neuroprotective effects of luteolin in MS are at a very preliminary stage as yet

The spherical three-dimensional model can be used for high-throughput screening experiments with high efficiency