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Likewise, there is its negative association (i.e., elevated egr-1 levels associated with cardiovascular pathobiology (Khachigian, 2006) or cholestatic liver injury (Kim et al., 2006

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Finally, if the serum cobalamin concentration at the time of reevaluation is subnormal, further work-up is required to definitively diagnose the underlying disease process and cobalamin supplementation should be continued weekly or bi-weekly (for parenteral supplementation) or daily (for oral supplementation)