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Interestingly, the effect of androgens on mitochondrial dynamics may be influenced by the metabolic status and dose of the exogenous androgen, for the failure of testosterone exposure to change these dynamics-related proteins (e.g., DRP1, OPA1, and MFN2) in the skeletal muscle of healthy young women (136)

In addition, CoQ10 acts as an antioxidant, protecting against neuroinflammation and cell death

CrossRef SGLT2 Inhibitors as Systemic Metabolic Modulators: Linking Glucose Excretion to Liver Function Restoration Seung Wan Noh, Han Sol Ryu, Yong-Ho Kim, Byung-Chul Oh Endocrinology and Metabolism.2025

doi: 10.1161/ATVBAHA.121.316862

Based on a previous work, 30 mg/kg was considered the dose sufficient to achieve a C max comparable to the L-carnitine concentration used in vitro (1 mM) 41