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Adipocyte Metabolism: Investigated for its ability to reduce white adipose tissue mass by shifting cellular metabolism away from storage and towards energy expenditure (without affecting food intake in murine models)

Additionally, the oral bioavailability observed in animal models makes the compound attractive for potential clinical development

Another aspect of the invention pertains to small molecule quinoline derived cations of Formula IA, wherein: the cation of Formula IA includes two or more non-hydrogen substituents, and wherein: R 5 is H or NH 2 , R 6 is H or F

This approach maintains consistent peptide signaling and metabolic effects throughout the treatment period

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