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Its discovery opened a new chapter in sleep science, establishing that the brain produces discrete peptide signals capable of modulating sleep architecture a concept that has since expanded into a broader field of sleep-regulatory neuropeptide research

The Nitric Oxide Pathway L-Citrulline works through the following pathway: [4] When consumed, L-citrulline bypasses the liver's first-pass metabolism and enters the bloodstream efficiently

& Hochstrasser, M

& Sadler, P

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