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GO and KEGG pathway analysis were performed based on the promoter-enriched peaks (or promoter-enriched differentially enriched regions) associated genes using the ClusterProfiler R package (v3.18.1)

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This stage of the disease is characterized by the deposition of solid urate (tophi) in the articular (cartilage covering the bony ends of the articulating joints) and other connective tissues

In our current strategy, we have used two fusion proteins, SUMO and eSrtA, between N-terminal His 6 -tag and C-terminal MT, and hence the chance of any influence of Ni 2+ -NTA on MTs is very low

Insulin-stimulated phosphorylation of the Rab GTPase-activating Protein TBC1D1 Regulates GLUT4 translocation